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Topic 1 : Carbon dioxide transport in the blood
1) BICARBONATE IONS (HCO3- )
This reaction also occurs outside the red blood cells, in the plasma, but is much slower due to the lack of carbonic anhydrase.
The hydrogen ions, formed from the dissociated carbonic acid, combine with the hemoglobin in the red blood cell.
2) BOUND TO HEMOGLOBIN AND PLASMA PROTEINS
3) DISSOLVED CO2
Topic 2 : Transport of Carbon DiOxide from Blood to Lung (Image B)
Bicarbonate ions enter the red blood cells and combine with hydrogen ions to form carbonic acid. This is broken down into carbon dioxide and water.
HCO3- + H+ --> H2CO3 --> CO2 + H2O
Carbon dioxide diffuses out of the red blood cells and into the alveoli which will be expired out.
Topic 3 : Bohrs Effect Vs Haldane Effect
Bohrs Effect: In Peripheral tissue , Increase in hydrogen from tissue metabolism shifts oxygen dissociation curve to the right & thus unloading Oxygen
Haldane Effect: In Lungs, Oxygynation of Hb promotes dissociation of Hydrogen ion from Hb & this shifts equilibrium toward Carbon Dioxide formation , therefore CO2 is released from RBCs.
Topic 4 : Clinical facts